Research & Expertise

Fall prevention in Parkinson’s, neurodegenerative disease and ageing

We are seeking to establish whether cognitive enhancement with cholinesterase inhibitors prevents people with Parkinson’s from falling. The £2.1 million NIHR funded CHIEF-PD trial builds on the foundational ReSPOND trial that we completed and published in Lancet Neurology in 2016.

Across 39 NHS hospital sites in the UK, we enrolled 600 people with Parkinson’s, making CHIEF-PD the largest trial of a novel drug treatment in Parkinson’s ever conducted in the UK. The data collection part of the trial has now come to an end and our team have begun to analyse the data.

Read more about the CHIEF-PD trial.

Improving Parkinson’s monitoring, treatment and care

Recognising that care for older people and those with Parkinson’s is often fragmented and reactive, we are trialling new ways of delivering care with cutting edge treatments and monitoring. The PRIME Parkinson programme is a £10 million programme of research that we are undertaking in collaboration with Prof Bas Bloem and Dr Marten Munneke at Radboud University, Netherlands.

As part of this programme, the PRIME Parkinson UK Randomised Controlled Trial (RCT) has recruited 214 people with Parkinson’s and many of their informal caregivers, who live in the catchment areas of the Royal United Hospitals, Bath, and aims to compare outcomes from usual care provided by the NHS with those from usual NHS care together with a new model of care, called PRIME Parkinson Care.

Read more about the PRIME-PD programme.

Transforming Training in Geriatric Medicine

We have developed an innovative undergraduate geriatrics curriculum which is delivered via an 18-week clerkship at the University of Bristol. Embedded within this is a mixed-methods programme of research to evaluate and innovate undergraduate teaching in geriatric medicine. This work, funded by The Dunhill Medical Trust, comprises three streams of work:

  • Innovation and Evaluation of the ‘Complex Medicine in Older People’ curriculum (CMOP) at Bristol Medical School
  • The Students and Trainees on Medical Placements (STOMP): Tackling Discrimination Study
  • The 3rd national BGS survey of undergraduate education in ageing and geriatric medicine

Read more about these programmes or follow us on Twitter @GerisMedEd @StompStudy.