Projects & Current Trials

Rivastigmine to Stabilisa Gait in Parkinson’s Disease: The ReSPonD Trial

Dr Henderson set up and executed this phase II, double blind randomised controlled trial as her PhD. This trial sought to determine whether the cholinesterase inhibitor, rivastigmine stabilised gait and balance to potentially reduce falls in people with Parkinson’s. The results were published in Lancet Neurology in 2016 and subsequently Dr Henderson is Chief Investigator on the £2.1 million NIHR funded CHIEF-PD trial which is recruiting at sites across the UK.


This phase III trial will determine the effectiveness of rivastigmine for falls prevention in Parkinson’s disease with cost-effectiveness analysis. It is currently recruiting 600 people with idiopathic Parkinson’s disease who have experienced a fall in the past year and who do not have dementia. More information about the trial, team and taking part is available here.


Phone: 0117 42 83113


PRIME Cross-sectional: A cross-sectional study of patients with parkinsonism, in the Bath area, and their caregivers

This study aims to describe a broad range of PwP in relation to their symptomatology, disability, health needs, disease stage, comorbidities and sociodemographics.  We will recruit PwP who are additionally living with frailty, multimorbidity and cognitive impairment, in order to describe a representative population and address this area of unmet need.  We are also co-enrolling individuals who live with, care for, or support someone with parkinsonism in order to gain vital information on the lived experience of caregivers. The results of this study will inform the development and delivery of the PRIME intervention within the PRIME RCT, as well providing a sampling frame for the PRIME RCT.

PRIME Epidemiology

– read more here

PRIME Randomised Control Trial

– read more here

STRIPEStimulation of the Tibial nerve Repetitively to Improve Incontinence in Parkinson’s disease Electronically: a randomised control trial of a novel self adhesive device to deliver tibial nerve stimulation for bladder symptoms associated with Parkinson’s disease.

Driving in Parkinson’s


STOMP: Tackling Discrmination

The Students and Trainees on Medical Placements (STOMP): Tackling Discrimination Study

A mixed-methods study exploring medical students’ experience of inappropriate and distressing behaviour from patients pertaining to the students’ protected characteristics, and the extent to which the training they receive at medical school empowers them to deal with and/or escalate these interactions appropriately.

Twitter: @StompStudy #STOMPStudy



Complex Medicine in Older People (CMOP) is an 18 week clerkship that takes place in the 4th year of study at Bristol Medical School. As the name implies, the clerkship is focussed on equipping tomorrow’s doctors with the knowledge and skills required to care for older people with complex health and social care needs.

Read more about the CMOP curriculum evaluation and innovation here

Twitter: @GerisMedEd #CMOPBookClub